依匹斯汀盐酸盐

  • 化学数据
CAS号 80012-44-8 货号 BCP09495
中文名 依匹斯汀盐酸盐
英文名 Epinastine hydrochloride
中文别名
英文别名 Alesion; Elestat; Epinastine HCl; Epinastin HCl;
分子式 C16H16ClN3 分子量 285.77
  • 用途
生物活性 Epinastine Hydrochloride is an histamine H1 receptor antagonist without sedative activity. Epinastine hydrochloride blocks the histamine H1 receptor and inhibits the release of histamine from mast cells. This prevents the typical allergic symptoms that are caused by histamine activity on capillaries, skin, mucous membranes. Typical histamine activities include vasodilation, bronchoconstriction, increased vascular permeability, pain, itching, and spasmodic contractions of gastrointestinal smooth muscles. Epinastine also has affinity for the histamine H2, 5-HT2, and the alpha-1, alpha-2 adrenergic receptors.
信号通路 Neuro Signaling Pathway GPCR/G Protein 
靶 点 Histamine Receptor 

结构式

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