比伐卢定
CAS号 | 128270-60-0 | 货号 | BCP02040 |
中文名 | 比伐卢定 | ||
英文名 | Bivalirudin | ||
中文别名 | 比瓦尔丁; | ||
英文别名 | BG-8967; BG 8967; BG8967;Hirulog; | ||
分子式 | C98H138N24O33 | 分子量 | 2180.29 |
生物活性 | Bivalirudin is a 20 amino acid long synthetic peptide with thrombin-specific anticoagulant properties. Bivalirudin reversibly binds thrombin, free as well as clot bound, at the catalytic site and the anion-binding exosite, thereby preventing the formation and activation of fibrin, factor XIIIa, and other coagulation factors. This drug is primarily used during coronary angioplasty procedures, in combination with aspirin, in patients with unstable angina. | ||
信号通路 | Protease/Metabolic Enzyme | ||
靶 点 | Thrombin |
结构式
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