LY411575
| CAS No. | 209984-57-6 | Cat. No. | BCP02531 |
| Name | LY411575 | ||
| Synonyms | LY 411575;LY-411575; LSN-411575; LSN 411575; LSN411575; | ||
| Formula | C26H23F2N3O4 | M. Wt | 479.48 |
| Description | LY 411575, also known as LSN-411575, is potent, cell permeable and selective γ-secretase inhibitor that reduces Aβ/42 after acute or chronic treatment, and blocks Notch activation. The gamma secretase inhibitor, activating pPKC alpha intracellular pathway could be suggested to prevent or reduce downstream toxic events, representing a useful strategy to counteract Alzheimer's disease. | ||
| Pathways | Protease/Metabolic Enzyme Neuro Signaling Pathway Wnt/Stem Cell | ||
| Targets | Gamma secretase Notch | ||
Structure
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