丁酸氯维地平
| CAS号 | 167221-71-8 | 货号 | BCP22687 |
| 中文名 | 丁酸氯维地平 | ||
| 英文名 | Cleviprex | ||
| 中文别名 | |||
| 英文别名 | Clevidipine butyrate; | ||
| 分子式 | C21H23Cl2NO6 | 分子量 | 456.32 |
| 生物活性 | Clevidipine is a dihydropyridine L-type calcium channel blocker, highly selective for vascular, as opposed to myocardial, smooth muscle and, therefore, has little or no effect on myocardial contractility or cardiac conduction. It reduces mean arterial blood pressure by decreasing systemic vascular resistance. Clevidipine does not reduce cardiac filling pressure, confirming lack of effects on the venous capacitance vessels. No increase in myocardial lactate production in coronary sinus blood has been seen, confirming the absence of myocardial ischemia due to coronary steal. | ||
| 信号通路 | Ion Channel/Membrane Transporter | ||
| 靶 点 | Calcium Channel | ||
结构式
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