Bexarotene

CAS No.	153559-49-0	Cat. No.	BCP04099
Name	Bexarotene
Synonyms	LGD1069;LGD 1069;LGD-1069; LG 100069; Ro 26-445; SR 11247; 3-methyl TTNEB;Targretin;
Formula	C24H28O2	M. Wt	348.48

Description	Bexarotene is a synthetic retinoic acid agent with potential antineoplastic, chemopreventive, teratogenic and embryotoxic properties. Bexarotene selectively binds to and activates retinoid X receptors (RXRs), thereby inducing changes in gene expression that lead to cell differentiation, decreased cell proliferation, apoptosis of some cancer cell types, and tumor regression.
Pathways	Protease/Metabolic Enzyme
Targets	RAR/RXR

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