环孢菌素 B
CAS号 | 63775-95-1 | 货号 | BCP04175 |
中文名 | 环孢菌素 B | ||
英文名 | Cyclosporin B | ||
中文别名 | |||
英文别名 | Cyclosporine Impurity-B; Antibiotic S 7481F2;CyclosporinB; | ||
分子式 | C61H109N11O12 | 分子量 | 1188.61 |
生物活性 | Cyclosporin B is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosuppressant activity. Cyclosporin B is a derivative of cyclosporin A that exhibits significantly less immunosuppressive activity. Cyclosporin B displays antiviral properties, inhibiting entry of hepatitis B into hepatocytes. Cyclosporin B also inhibits RANKL-induced TRAP phosphatase activity, inducing apoptosis in osteoclasts. | ||
信号通路 | Others Pathway | ||
靶 点 | Others |
结构式
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