维替泊芬
| CAS号 | 129497-78-5 | 货号 | BCP04238 |
| 中文名 | 维替泊芬 | ||
| 英文名 | Verteporfin | ||
| 中文别名 | 维替卟吩;维替铂芬; | ||
| 英文别名 | CL 318952;CL318952;CL-318952;BPD-MA; | ||
| 分子式 | C41H42N4O8 | 分子量 | 718.79 |
| 生物活性 | Verteporfin is a potent second-generation photosensitizing agent derived from porphyrin. It is used as a photosensitizer for photodynamic therapy to eliminate abnormal blood vessels in the eye that are associated with conditions such as macular degeneration. Verteporfin also suppresses the formation of autophagosome via targeting p62, which binds both polyubiquitinated proteins destined for degradation and LC3 on autophagosomal membranes. | ||
| 信号通路 | Angiogenesis/Protein Tyrosine Kinase | ||
| 靶 点 | VDA | ||
结构式
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