5-氨基水杨酸
| CAS号 | 89-57-6 | 货号 | BCP05326 |
| 中文名 | 5-氨基水杨酸 | ||
| 英文名 | 5-Aminosalicylic acid | ||
| 中文别名 | 美沙拉嗪; | ||
| 英文别名 | Mesalamine; Asacol; Z-206; 5-ASA; AJG-501; MAX-002; Z 206; 5 ASA; AJG 501; MAX 002; Z206; 5ASA; AJG501; MAX002; | ||
| 分子式 | C7H7NO3 | 分子量 | 153.14 |
| 生物活性 | 5-aminosalicylic acid (5-ASA), also known as mesalamine or Mesalazine is an anti-inflammatory drug used to treat inflammatory bowel disease, such as ulcerative colitis and mild-to-moderate Crohn's disease. Mesalazine is a bowel-specific aminosalicylate drug that acts locally in the gut and has its predominant actions there, thereby having few systemic side effects. As a derivative of salicylic acid, mesalazine is also thought to be an antioxidant that traps free radicals, which are potentially damaging byproducts of metabolism. Mesalazine is the active moiety of sulfasalazine, which is metabolized to sulfapyridine and mesalazine. Mesalazine is the active component of the prodrug balsalazide along with the inert carrier molecule 4-aminobenzoyl-beta-alanine. | ||
| 信号通路 | Cell Cycle/DNA Damage NFκB | ||
| 靶 点 | NF κB PPAR PAK | ||
结构式
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