索氟布韦
CAS号 | 1190307-88-0 | 货号 | BCP06035 |
中文名 | 索氟布韦 | ||
英文名 | Sofosbuvir | ||
中文别名 | 索非布韦; | ||
英文别名 | PSI 7977;PSI-7977;PSI7977; GS7977; GS-7977; GS 7977; | ||
分子式 | C22H29FN3O9P | 分子量 | 529.45 |
生物活性 | PSI-7851 is a mixture of two similar molecules, PSI-7976 and PSI-7977, which exist in PSI-7851 as isomers of each other. Once inside a liver cell, both molecules are rapidly converted to the same active triphosphate. Given the ability to more easily manufacture PSI-7977, and potentially advantageous in vitro characteristics, PSI-7977 was selected for further clinical development. | ||
信号通路 | Microbiology/Virology Cell Cycle/DNA Damage | ||
靶 点 | DNA/RNA Synthesis HCV |
Different Interaction Profiles of Direct-Acting Anti-Hepatitis C Virus Agents with Human Organic Anion Transporting Polypeptides
购于瀚香生物(Biochempartner)的索氟布韦(CAS:1190307-88-0)被引用 |
结构式
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