S0859

  • 化学数据
CAS号 1019331-10-2 货号 BCP06882
中文名 S0859
英文名 S0859
中文别名
英文别名 S 0859;S-0859;
分子式 C29H24ClN3O3S 分子量 530.04
  • 用途
生物活性 S0859 is a selective, high-affinity generic NBC inhibitor, potentially important for probing the transporter's functional role in heart and other tissues. S0859 reversibly inhibited NBC-mediated pH(i) recovery (K (i)=1.7 microM, full inhibition at approximately 30 microM). In HEPES-buffered superfusates, NHE-mediated pH(i) recovery was unaffected by 30 microM S0859. With CO(2)/HCO(3) (-) buffer, pH(i) recovery from intracellular alkalosis (mediated by Cl(-)/HCO(3) (-) and Cl(-)/OH(-) exchange) was also unaffected.
信号通路 Others Pathway 
靶 点 Others 

结构式

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