吡嘧司特钾
| CAS号 | 100299-08-9 | 货号 | BCP21138 |
| 中文名 | 吡嘧司特钾 | ||
| 英文名 | Pemirolast potassium | ||
| 中文别名 | 吡嘧司特钾水合物;毗嘧司特钾;嘧司特钾; | ||
| 英文别名 | Pemirolast potassium salt;BMY 26517; TWT8152; BMY 26517;TWT-8152; BMY 26517; TWT8152; | ||
| 分子式 | C10H7KN6O | 分子量 | 266.31 |
| 生物活性 | Pemirolast Potassium is the potassium salt form of pemirolast, a pyrimidinone derivative with antiallergic property. Pemirolast potassium exerts its action by blocking the antigen-mediated calcium ion influx into mast cells. This prevents mast cell degranulation, resulting in mast cell stabilization and inhibition of the release of inflammatory mediators, histamine and leukotrienes, which are involved in the allergic process. Pemirolast potassium also prevents inflammatory mediator release from eosinophils. | ||
| 信号通路 | Neuro Signaling Pathway GPCR/G Protein | ||
| 靶 点 | Histamine Receptor | ||
结构式
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