广藿香酮

化学数据

CAS号	23800-56-8	货号	BCP49696
中文名	广藿香酮
英文名	Pogostone
中文别名	异香附酮;4-羟基-6-甲基-3-(4-甲基-1-氧代戊基)-2H-吡喃-2-酮;
英文别名	Dhelwangin;4-Hydroxy-6-methyl-3-(4-methyl-1-oxopentyl)-2H-pyran-2-one;
分子式	C12H16O4	分子量	224.25

用途

生物活性	Pogostone, isolated from the herbs of Pogostemon cablin (Blanco) Benth, possesses potent anti-bacterial and anti-fungal activities and has been used for the quality control of essential oil of Pogostemon cablin. It could inhibit both gram negative bacteria (0.098-1 600 µg/ml) and gram positive bacteria (0.098-800 µg/ml). Besides, Pogostone could exert a gastro-protective effect against gastric ulceration, and the underlying mechanism might be associated with the stimulation of PGE2, improvement of antioxidant and anti-inflammatory status, as well as preservation of NP-SH. Pogostone exhibited an immunosuppressive property by directly blocking T cell proliferation as well as altering inflammatory cytokine profile.

生物活性

Pogostone, isolated from the herbs of Pogostemon cablin (Blanco) Benth, possesses potent anti-bacterial and anti-fungal activities and has been used for the quality control of essential oil of Pogostemon cablin. It could inhibit both gram negative bacteria (0.098-1 600 µg/ml) and gram positive bacteria (0.098-800 µg/ml). Besides, Pogostone could exert a gastro-protective effect against gastric ulceration, and the underlying mechanism might be associated with the stimulation of PGE2, improvement of antioxidant and anti-inflammatory status, as well as preservation of NP-SH. Pogostone exhibited an immunosuppressive property by directly blocking T cell proliferation as well as altering inflammatory cytokine profile.

结构式

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