ASP2453
| CAS No. | 2241719-73-1 | Cat. No. | BCP48490 |
| Name | ASP2453 | ||
| Synonyms | ASP 2453; ASP-2453; | ||
| Formula | C40H48F3N7O4 | M. Wt | 747.85 |
| Description | ASP2453 is a potent, selective and covalent KRAS G12C inhibitor. ASP2453 inhibits the Son of Sevenless (SOS)-mediated interaction between KRAS G12C and Raf with an IC50 value of 40 nM. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Ras/Rho | ||
Structure
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