二甲双胍
CAS号 | 657-24-9 | 货号 | BCP48284 |
中文名 | 二甲双胍 | ||
英文名 | Metformin | ||
中文别名 | 双甲胍;1,1-二甲基双胍; | ||
英文别名 | 1,1-Dimethylbiguanide;Fluamine; | ||
分子式 | C4H11N5 | 分子量 | 129.16 |
生物活性 | Metformin is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity. Metformin is associated with a very low incidence of lactic acidosis. This agent helps reduce LDL cholesterol and triglyceride levels, and is not associated with weight gain, and prevents the cardiovascular complications of diabetes. Metformin is not metabolized and is excreted unchanged by the kidneys. | ||
信号通路 | PI3K/Akt/mTOR Epigenetics | ||
靶 点 | AMPK |
结构式
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