N106
| CAS No. | 862974-25-2 | Cat. No. | BCP48201 |
| Name | N106 | ||
| Synonyms | N-106; N 106; | ||
| Formula | C17H14N4O3S | M. Wt | 354.38 |
| Description | N106 directly activates the SUMO-activating enzyme, E1 ligase, and triggers intrinsic SUMOylation of SERCA2a. Decreased activity and expression of the cardiac sarcoplasmic reticulum calcium ATPase (SERCA2a), a critical pump regulating calcium cycling in cardiomyocyte, are hallmarks of heart failure. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | Calcium Channel | ||
Structure
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