TCS 46B
| CAS No. | 302799-86-6 | Cat. No. | BCP48090 |
| Name | TCS 46B | ||
| Synonyms | 1,3-Dihydro-5-[3-[4-(phenylmethyl)-1-2H-benzimidazol-2-one; | ||
| Formula | C22H23N3O | M. Wt | 345.44 |
| Description | TCS 46b is a subtype-selective NR1A/NR2B NMDA receptor antagonist (IC50 = 5.3, 35000 and > 100000 nM for NR1A/2B, NR1A/2A and NR1A/2C receptor subtypes, respectively). TCS 46b potentiates the effect of L-DOPA in 6-OHDA-lesioned rats following oral administration. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | AMPA/NMDA | ||
Structure
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