CAY10462
CAS号 | 502656-68-0 | 货号 | BCP48084 |
中文名 | CAY10462 | ||
英文名 | CAY10462 | ||
中文别名 | |||
英文别名 | CAY 10462;CAY-10462; | ||
分子式 | C17H25N3O.2HCl | 分子量 | 360.32 |
生物活性 | 20-HETE is an important metabolite of arachidonic acid in the vasculature, especially in the kidney, where it is synthesized by cytochrome P450 (CYP450) enzymes of the 4A family. CAY10462 is the hydrochloride salt form of CAY10434. It is a selective inhibitor of the 20-HETE synthase CYP4A11, which exhibits an IC50 of 8.8 nM when tested in human renal microsomes. | ||
上下游产品 | 769917-29-5(CAY10434) | ||
信号通路 | Protease/Metabolic Enzyme | ||
靶 点 | Cytochrome P450 |
结构式
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