Box5
CAS号 | 881188-48-3 | 货号 | BCP46893 |
中文名 | Box5 | ||
英文名 | Box5 | ||
中文别名 | |||
英文别名 | Box-5;Box 5; | ||
分子式 | C25H42N6O11S2 | 分子量 | 666.76 |
生物活性 | Box5 is a Wnt5a-derived N-butyloxycarbonyl hexapeptide (t-Boc-Met-Asp-Gly-Cys-Glu-Leu), acts as an Wnt5a antagonist; abolishes exogenous Wnt5a stimulation of A2058 cells increased adhesion, migration and invasion, all crucial components of tumor metastasis, also inhibits the basal migration and invasion of Wnt5a-expressing HTB63 melanoma cells, antagonizes the effects of Wnt5a on melanoma cell migration and invasion by directly inhibiting Wnt5a-induced PKC and Ca(2+) signaling. | ||
信号通路 | Wnt/Stem Cell | ||
靶 点 | Wnt |
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服:
- 全国免费电话:400-099-8200
瀚香生物(Biochempartner) 的所有产品和服务仅用于科学研究,禁止用于人体和治疗!