M4076

  • Chemical Properties
CAS No. 2495096-26-7 Cat. No. BCP46441
Name M4076
Synonyms M-4076;M 4076;
Formula C23H21FN6O3 M. Wt 448.45
  • Biological Activity
Description M4076 is an ATP-competitive inhibitor of the Ataxia telangiectasia mutated (ATM) kinase with IC50 of 0.2 nM, which targets tumor cell survival and growth by inhibiting double-strand break (DSB) repair as well as checkpoint control.
Pathways Cell Cycle/DNA Damage 
Targets ATM/ATR 

Structure

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