盐酸维那卡兰
CAS号 | 748810-28-8 | 货号 | BCP45728 |
中文名 | 盐酸维那卡兰 | ||
英文名 | Vernakalant hydrochloride | ||
中文别名 | 盐酸弗纳卡兰;盐酸维纳卡兰; | ||
英文别名 | Vernakalant HCl;RSD1235 hydrochloride; | ||
分子式 | C20H32ClNO4 | 分子量 | 385.93 |
生物活性 | Vernakalant HCl is an investigational drug for the acute conversion of atrial fibrillation. Like other class III antiarrhythmics, vernakalant blocks atrial potassium channels, thereby prolonging repolarization. It differs from typical class III agents by blocking a certain type of potassium channel, the cardiac transient outward potassium current, with increased potency as the heart rate increases. This means that it is more effective at high heart rates, while other class III agents tend to lose effectiveness under these circumstances. It also slightly blocks the hERG potassium channel, leading to a prolonged QT interval. Vernakalant also blocks atrial sodium channels. | ||
信号通路 | Ion Channel/Membrane Transporter | ||
靶 点 | Potassium Channel |
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服:
- 全国免费电话:400-099-8200
瀚香生物(Biochempartner) 的所有产品和服务仅用于科学研究,禁止用于人体和治疗!