CNQX
CAS号 | 115066-14-3 | 货号 | BCP44343 |
中文名 | CNQX | ||
英文名 | CNQX | ||
中文别名 | |||
英文别名 | FG9065;FG-9065;FG 9065; | ||
分子式 | C9H4N4O4 | 分子量 | 232.15 |
生物活性 | CNQX is an AMPA and kainate receptor antagonist (IC50 values are 0.3 and 1.5 μM for AMPA and kainate receptors, respectively). CNQX is also an antagonist at the glycine modulatory site on the NMDA receptor complex (IC50 = 25 μM). CNQX can be used to isolate GABAA receptor-mediated spontaneous inhibitory postsynaptic currents and antagonizes non-NMDA receptor-mediated responses in cultured cerebellar granule cells. CNQX shows neuroprotective effects in models of ischemia and inhibits seizure-like activity in hippocampal neurons. | ||
上下游产品 | 479347-85-8(CNQX disodium salt ) | ||
信号通路 | Ion Channel/Membrane Transporter | ||
靶 点 | AMPA/NMDA |
结构式
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