Levalbuterol hydrochloride

  • Chemical Properties
CAS No. 50293-90-8‬ Cat. No. BCP44201
Name Levalbuterol hydrochloride
Synonyms Levalbuterol HCl;R-albuterol hydrochloride;
Formula C13H22ClNO3 M. Wt 275.77
  • Biological Activity
Description Levalbuterol Hydrochloride is the hydrochloride salt form of levalbuterol, a relatively selective sympathomimetic beta-2 adrenergic receptor agonist with bronchodilator activity. Levalbuterol hydrochloride binds to beta-2 adrenergic receptors in bronchial smooth muscle and activates intracellular adenyl cyclase, thereby increasing the production of cyclic-3', 5'-adenosine monophosphate (cAMP). Increased cAMP levels lead to the activation of protein kinase A, which inhibits the phosphorylation of myosin and lowers intracellular ionic calcium concentrations, resulting in relaxation of bronchial smooth muscles. The increased cyclic AMP concentrations also inhibit the release of inflammatory mediators from mast cells.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets Adrenergic Receptor 

Structure

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