Lenrispodun phosphate

  • 化学数据
CAS号 1642303-38-5 货号 BCP44187
中文名 Lenrispodun phosphate
英文名 Lenrispodun phosphate
中文别名
英文别名 ITI-214; ITI 214; ITI214; ITI-214 phosphate salt;PDE1-IN-1 phosphate;ITI-214 phosphate;
分子式 C29H29FN7O5P 分子量 605.57
  • 用途
生物活性 ITI-214 is an orally active, potent and Selective Inhibitors of Phosphodiesterase 1 for the Treatment of Cognitive Impairment Associated with Neurodegenerative and Neuropsychiatric Diseases. ITI-214 exhibited picomolar inhibitory potency for PDE1, demonstrated excellent selectivity against all other PDE families, and showed good efficacy in vivo. Currently, this investigational new drug is in Phase I clinical development and being considered for the treatment of several indications including cognitive deficits associated with schizophrenia and Alzheimer's disease, movement disorders, attention deficit and hyperactivity disorders, and other CNS and non-CNS disorders.
上下游产品 1160521-50-5(Lenrispodun)
信号通路 Protease/Metabolic Enzyme 
靶 点 Phosphodiesterase/PDE 

结构式

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