Indirubin-3'-oxime

  • 化学数据
CAS号 667463-82-3 货号 BCP43705
中文名 Indirubin-3'-oxime
英文名 Indirubin-3'-oxime
中文别名
英文别名 Indirubin-3'-monoxime;IDR3O; I3O;
分子式 C16H11N3O2 分子量 277.28
  • 用途
生物活性 Indirubin-3'-monoxime is a member of the class of biindoles that is indirubin in which the keto group at position 3' has undergone condensation with hydroxylamine to form the corresponding oxime. It has a role as an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor, an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor, an osteogenesis regulator, a neuroprotective agent and an anti-obesity agent. It is a member of oxindoles, a bisindole, a ring assembly, a ketoxime and an alkaloid.
信号通路 Cell Cycle/DNA Damage Wnt/Stem Cell PI3K/Akt/mTOR MAPK Pathway 
靶 点 GSK3 JNK CDK 

结构式

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