SRT2183

  • 化学数据
CAS号 1001908-89-9 货号 BCP37408
中文名 SRT2183
英文名 SRT2183
中文别名
英文别名 SRT 2183; SRT-2183;
分子式 C27H24N4O2S 分子量 468.57
  • 用途
生物活性 SRT2183 is a Sirt1 activator, currently being developed by Sirtris Pharmaceuticals. SRT2183 has similar activity in the body to another SIRT1 activator SRT1720 , but is closer in potency to resveratrol. In animal studies it was found to improve insulin sensitivity and lower plasma glucose levels in fat, muscle and liver tissue, and increased mitochondrial and metabolic function. However, the claim that SRT2183 is a SIRT1 activator has been questioned and further defended.
信号通路 Cell Cycle/DNA Damage Epigenetics 
靶 点 Sirtuin 

结构式

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