Marinopyrrole A
| CAS号 | 1227962-62-0 | 货号 | BCP36069 |
| 中文名 | Marinopyrrole A | ||
| 英文名 | Marinopyrrole A | ||
| 中文别名 | |||
| 英文别名 | Maritoclax; (±)-Marinopyrrole; | ||
| 分子式 | C22H12Cl4N2O4 | 分子量 | 510.15 |
| 生物活性 | Marinopyrrole A cytotoxicity is assessed by seeding 2×104 HeLa or L929 cells per well in sterile 96-well tissue culture-treated plates. After 24 h, the medium is replaced with fresh medium containing increasing concentrations of marinopyrrole A, and the plates are incubated at 37°C in 5% CO2 for 24 h. Cytotoxicity is assayed at 24 h by measuring the reduction of MTS [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium] using the CellTiter 96 Aqueous nonradioactive cell proliferation assay according to the manufacturer's instructions. | ||
| 信号通路 | Apoptosis Pathway | ||
| 靶 点 | Bcl2 | ||
结构式
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