Clobenpropit dihydrobromide

  • Chemical Properties
CAS No. 145231-35-2 Cat. No. BCP33039
Name Clobenpropit dihydrobromide
Synonyms
Formula C14H17ClN4S.2BrH M. Wt 470.66
  • Biological Activity
Description Clobenpropit dihydrobromide is a hydrobromide salt obtained by reaction of clobenpropit with two equivalents of hydrobromic acid. An extremely potent histamine H3 antagonist/inverse agonist (pA2 = 9.93). Also displays partial agonist activity at H4 receptors; induces eosinophil shape change with an EC50 of 3 nM. It has a role as a H4-receptor agonist and a H3-receptor antagonist. It contains a clobenpropit(2+).
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets Histamine Receptor 

Structure

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