依曲替酯
CAS号 | 54350-48-0 | 货号 | BCP31125 |
中文名 | 依曲替酯 | ||
英文名 | Etretinate | ||
中文别名 | 阿维A酸杂质B;维甲灵; | ||
英文别名 | HSDB 7185; HSDB7185; HSDB-7185; NSC 297936; NSC297936; NSC-297936; Ro 10-9359; Ro 10 9359; Ro109359; | ||
分子式 | C23H30O3 | 分子量 | 354.49 |
生物活性 | Etretinate is a synthetic oral retinoid that is a prodrug of acitretin. Etretinate activates retinoid receptors, causing an induction of cell differentiation, inhibition of cell proliferation, and inhibition of tissue infiltration by inflammatory cells. Etretinate is no longer commercially available in the U.S. due to the extended potential for teratogenic effects related to its long half-life. | ||
信号通路 | Protease/Metabolic Enzyme | ||
靶 点 | RAR/RXR |
结构式
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