ITX-5061 HCl
CAS号 | 1252679-52-9 | 货号 | BCP30784 |
中文名 | ITX-5061 HCl | ||
英文名 | ITX-5061 HCl | ||
中文别名 | |||
英文别名 | ITX-5061 hydrochloride ; ITX 5061 HCl ; ITX506 HCl;ITX5061 hydrochloride;ITX 5061 hydrochloride; | ||
分子式 | C30H38ClN3O7S | 分子量 | 620.16 |
生物活性 | ITX-5061 is a Hepatitis C Virus Entry Inhibitor or a scavenger receptor B1 antagonist. ITX 5061 has entered phase 1 clinical trials in hepatitis C virus (HCV)-infected humans. ITX-5061 possesses a unique mechanism of action that prevents the hepatitis C virus from entering liver cells and has demonstrated potent preclinical antiviral activity against all HCV genotypes. Preclinical studies have shown ITX-5061 to be a potent and selective inhibitor of HCV entry into hepatocytes, capable of preventing virus binding/fusion and cell to cell spread, suggesting ITX-5061 may reduce re-infection rates following liver transplant. | ||
信号通路 | Microbiology/Virology MAPK Pathway | ||
靶 点 | p38 MAPK HCV |
结构式
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