LUT-014
CAS号 | 2274819-46-2 | 货号 | BCP30636 |
中文名 | LUT-014 | ||
英文名 | LUT-014 | ||
中文别名 | |||
英文别名 | LUT 014;LUT014; | ||
分子式 | C27H19F3N8O | 分子量 | 528.50 |
生物活性 | LUT014 is a topical B-Raf Inhibitor, a proprietary, first-in-class, small molecule allowing administration of EGFR (Epidermal Growth Factor Receptor) Inhibitors to patients without interruptions caused by typical cutaneous side effects.Leveraging the paradoxical effect of B-Raf Inhibitors, LUT014 decreases dermal toxicities associated with EGFR Inhibitors, thus reducing acneiform lesions associated with such therapy. | ||
信号通路 | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway MAPK Pathway | ||
靶 点 | EGFR Raf |
结构式
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