莫非赛定
| CAS号 | 1092970-12-1 | 货号 | BCP29837 |
| 中文名 | 莫非赛定 | ||
| 英文名 | Morphothiadin（GLS4） | ||
| 中文别名 | |||
| 英文别名 | GLS4; GLS-4; GLS 4; | ||
| 分子式 | C21H22BrFN4O3S | 分子量 | 509.39 |
| 生物活性 | Morphothiadin, also known GLS4, is a potent and selective inhibitor of hepatitis B virus. GLS4 demonstrated potent inhibitory activities in HBV HepG2.2.15 cell assay with an EC50 value of 1nM, and it also exhibited high potency against various drug-resistant HBV viral strains with EC50 values in the range of 10-20nM, more potent than the typical HBV polymerase inhibitors such as lamivudine, telbivudine, and entecavir. Pharmacokinetic profiles of GLS4 were favorable and safety evaluation including acute toxicity and repeated toxicity study indicated that GLS4 was safe enough to support clinical experiments in human. | ||
| 上下游产品 | Mmethanesulfonate （甲磺酸莫非赛定） | ||
| 信号通路 | Microbiology/Virology | ||
| 靶 点 | HBV | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！