WM-1119
| CAS No. | 2055397-28-7 | Cat. No. | BCP29433 |
| Name | WM-1119 | ||
| Synonyms | MOZ-IN-1; WM 1119; WM1119; | ||
| Formula | C18H13F2N3O3S | M. Wt | 389.38 |
| Description | WM-1119 is a highly potent, selective inhibitor of lysine acetyltransferase KAT6A with Kd of 2 nM, WM-1119 is a reversible competitor of acetyl coenzyme A and inhibits MYST-catalysed histone acetylation. WM-1119 induces cell cycle exit and cellular senescence without causing DNA damage. WM-1119 arrests the progression of lymphoma in mice. | ||
| Pathways | Epigenetics | ||
| Targets | Histone Acetyltransferase | ||
Structure
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