MIK 665
| CAS号 | 1799631-75-6 | 货号 | BCP29223 |
| 中文名 | MIK 665 | ||
| 英文名 | MIK 665 | ||
| 中文别名 | |||
| 英文别名 | MIK-665; MIK665; S 64315; S-64315; S64315; | ||
| 分子式 | C47H44ClFN6O6S | 分子量 | 875.41 |
| 生物活性 | MIK665, also known as S 64315, is an inhibitor of induced myeloid leukemia cell differentiation protein (Mcl-1; Bcl2-L-3), with potential pro-apoptotic and antineoplastic activities. Upon administration, MIK665 binds to and inhibits the activity of Mcl-1, which promotes apoptosis of cells overexpressing Mcl-1. Mcl-1, an anti-apoptotic protein belonging to the Bcl-2 family of proteins, is upregulated in cancer cells and promotes tumor cell survival | ||
| 上下游产品 | 1799831-02-9（(R)-MIK665） | ||
| 信号通路 | Apoptosis Pathway | ||
| 靶 点 | Bcl2 | ||
结构式
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