INF-39

  • Chemical Properties
CAS No. 866028-26-4 Cat. No. BCP28974
Name INF-39
Synonyms INF39; INF 39;
Formula C12H13ClO2 M. Wt 224.684
  • Biological Activity
Description INF39 is a nontoxic, irreversible NLRP3 inhibitor able to decrease interleukin-1β release from macrophages. INF39 Targets the NLRP3 Inflammasome, and may be useful for the Treatment of Inflammatory Bowel Disease. Bioluminescence resonance energy transfer experiments proved that INF39 was able to directly interfere with NLRP3 activation in cells.
Pathways Others Pathway 
Targets NLR 

Structure

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