人参皂苷 RH2
CAS号 | 78214-33-2 | 货号 | BCP23574 |
中文名 | 人参皂苷 RH2 | ||
英文名 | Ginsenoside Rh2 | ||
中文别名 | 人参皂苷 R-RH2; | ||
英文别名 | 20(S)-Ginsenoside Rh2; 20(S)-Rh2; Ginsenoside-Rh2; | ||
分子式 | C36H62O8 | 分子量 | 622.87 |
生物活性 | Ginsenoside Rh2 is isolated from the root of Ginseng. Ginsenoside Rh2 induces the activation of caspase-8 and caspase-9. Ginsenoside Rh2 induces cancer cell apoptosis in a multi-path manner.(20S)-ginsenoside Rh2 is a ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 3 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position. It has a role as a plant metabolite, an antineoplastic agent, an apoptosis inducer, a cardioprotective agent, a bone density conservation agent and a hepatoprotective agent. It is a beta-D-glucoside, a 12beta-hydroxy steroid, a ginsenoside, a tetracyclic triterpenoid and a 20-hydroxy steroid. It derives from a hydride of a dammarane. | ||
信号通路 | Protease/Metabolic Enzyme Apoptosis Pathway | ||
靶 点 | Apoptosis Inducer Caspase |
结构式
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