多格列艾汀
| CAS号 | 1191995-00-2 | 货号 | BCP20539 |
| 中文名 | 多格列艾汀 | ||
| 英文名 | Dorzagliatin | ||
| 中文别名 | 多扎格列艾汀; | ||
| 英文别名 | Sinogliatin; HMS 5552; HMS-5552; HMS5552; RO5305552; RO-5305552; RO 5305552; | ||
| 分子式 | C22H27ClN4O5 | 分子量 | 462.93 |
| 生物活性 | Dorzagliatin, also known as HMS 5552, RO5305552 and sinogliatin, is a novel Dual-Acting Glucokinase Activator, which Improves Glycaemic Control and Pancreatic β-Cell Function in Patients With Type 2 Diabetes. By addressing the defect of the glucose sensor function of glucokinase, dorzagliatin has the potential to restore the impaired glucose homeostasis state of people with type 2 diabetes and serve as a first-line standard-of-care therapy for the treatment of the disease, or as a cornerstone therapy when taken in combination with currently approved anti-diabetes drugs. | ||
| 信号通路 | Protease/Metabolic Enzyme | ||
| 靶 点 | Glucokinase | ||
结构式
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