Home   >  
MAPK Pathway
  >  
MEK/ERK

Classified by application

All Products

Signaling Pathways

Research Areas

Nature products

Antibodies

Peptides

Catalysts

Impurities

Intermediate

Raw Materials

MEK/ERK

Chemical Structure Cat. No. Product Name CAS No.
APS-2-79 Chemical Structure
 BCP24938 APS-2-79 2002381-25-9
APS-2-79 is a KSR-dependent MEK antagonist. APS-2-79 inhibits ATPbiotin binding to KSR2 within the KSR2-MEK1 complexe with an IC50 of 120 nM. APS-2-79 makes the stabilization of the KSR inactive state antagonizes oncogenic Ras-MAPK signaling.
Selumetinib sulfate Chemical Structure
 BCP36547 Selumetinib sulfate 943332-08-9
Selumetinib Sulfate is the sulfate salt of selumetinib, an orally active, small molecule with potential antineoplastic activity.
ASN007 benzenesulfonate Chemical Structure
 BCP48484 ASN007 benzenesulfonate 2055597-39-0
ERK-IN-3 benzenesulfonate is a potent and orally active inhibitor of ERK. ERK-IN-3 benzenesulfonate inhibits ERK1/2 with low single-digit nM IC50 values. ERK-IN-3 benzenesulfonate can be used for the research of cancers driven by RAS mutations.
ASN007 Chemical Structure
 BCP48479 ASN007 2055597-12-9
ASN007 is a potent and oral of ERK. ASN007 inhibits ERK1/2 with low single-digit nM IC50 values. ASN007 has the potential to be used to study cancers driven by RAS mutations.
ONC-201 Dihydrochloride Chemical Structure
 BCP46830 ONC-201 Dihydrochloride 1638178-82-1
ONC-201, also known as TIC10, is a potent, orally active, and stable small molecule that transcriptionally induces TRAIL in a p53-independent manner and crosses the blood-brain barrier.
PD184161 Chemical Structure
 BCP46466 PD184161 212631-67-9
PD184161 is an orally active MEK inhibitor. PD184161 inhibits MEK activity (IC50=10-100 nM) in a time- and concentration-dependent manner. PD184161 inhibits cell proliferation and induces apoptosis. PD184161 produces depressive-like behavior.
Rineterkib hydrochloride Chemical Structure
 BCP43938 Rineterkib hydrochloride 1715025-34-5
Rineterkib is a RAF and ERK1/2 inhibitor which has demonstrated preclinical activity in multiple MAPK activated cancer cells and xenograft models.
BAY-885 Chemical Structure
 BCP34724 BAY-885 2307249-33-6
BAY-885 is a highly potent and selective ERK5 inhibitor.
Rineterkib Chemical Structure
 BCP38204 Rineterkib 1715025-32-3
Rineterkib is a RAF and ERK1/2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway.
trans-Zeatin Hydrochloride Chemical Structure
 BCP36686 trans-Zeatin Hydrochloride 6025-81-6
trans-Zeatin Hydrochloride can be used in biological study and therapeutic use for plant-growth factors as cell-proliferating agents for promotion of wound healing.
123下一页末页共 80 条记录 1 / 8 页 
0086-13720134139