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Factor Xa

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Factor Xa

Chemical Structure Cat. No. Product Name CAS No.
MK-2060 Chemical Structure
 BCP49317 MK-2060 MK-2060
MK-2060 is a novel inhibitor of Factor XI being investigated for the prevention of thrombosis in patients with end-stage renal disease (ESRD).
Razaxaban Chemical Structure
 BCP24153 Razaxaban 218298-21-6
Razaxaban is a highly potent, selective, and orally bioavailable factor Xa (FXa) inhibitor with Ki of o.19 nM, >5,000-fold selectivity over a series of related serine proteases.
Heparin sodium Chemical Structure
 BCP25408 Heparin sodium 9041-08-1
Heparin sodium, as as anti-coagulants, belongs to a class of glucans, which can interact with a variety of proteins to produce a variety of biological activities. Heparin sodium is routinely use for preventing the deep venous thrombosis in medical and surgical patients.
Asundexian Chemical Structure
 BCP46980 Asundexian 2064121-65-7
Asundexian (BAY 2433334; BI1265162) is an orally active coagulation factor Xia (FXIa) inhibitor. BAY 2433334 inhibits human FXIa in buffer with an IC50 of 1 nM.
Darexaban Chemical Structure
 BCP45981 Darexaban 365462-23-3
Darexaban is a potent, selective and orally active factor Xa (FXa) inhibitor with an IC50 of 54.6 nM. Darexaban shows high selectivity against other related serine proteases, such as trypsin, thrombin, and kallikrein. Darexaban has anticoagulant and antithrombotic effects.
BMS-262084 Chemical Structure
 BCP45717 BMS-262084 253174-92-4
BMS 262084 is a potent and selective azetidinone-based beta-lactam tryptase inhibitor.
Edoxaban Chemical Structure
 BCP38288 Edoxaban 912273-65-5
Edoxaban is an orally active inhibitor of coagulation factor Xa (activated factor X) with anticoagulant activity. Edoxaban is administered as edoxaban tosylate. This agent has an elimination half-life of 9-11 hours and undergoes renal excretion.
BMS-962212 Chemical Structure
 BCP31167 BMS-962212 1430114-34-3
BMS-962212 is a reversible, direct, and highly selective inhibitor of FXIa.
BMS-740808 Chemical Structure
 BCP23400 BMS-740808 280118-23-2
BMS-740808 is a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor Xa.
Betrixaban maleate Chemical Structure
 BCP25697 Betrixaban maleate 936539-80-9
Betrixaban is a highly potent, selective, and orally efficacious factor Xa inhibitor with IC50 of 1.2 nM(inhibition of Factor 10a).
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