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DNA PK

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DNA PK

Chemical Structure Cat. No. Product Name CAS No.
BAY8400 Chemical Structure
 BCP44636 BAY8400 BAY8400
BAY-8400 is an orally active, potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (IC50=81 nM). BAY-8400 can be used for the research of cancer.
6-Nitroveratraldehyde Chemical Structure
 BCP37748 6-Nitroveratraldehyde 20357-25-9
6-Nitroveratraldehyde is a derivative of vanillin with 100-fold potency compared to vanillin, and acts as an inhibitor of DNA-dependent protein kinase (DNA-PK) (IC50 = 15 μM).
Lturm34 Chemical Structure
 BCP36071 Lturm34 1879887-96-3
LTURM34 is a novel potent and selective DNA-PK inhibitor, attenuating proliferation of a wide range of tumor cell lines in vitro.
AZD-7648 Chemical Structure
 BCP30676 AZD-7648 2230820-11-6
AZD-7648 is a potent and highly selective DNA-PK inhibitor.
Nedisertib Chemical Structure
 BCP30542 Nedisertib 1637542-33-6
Nedisertib (M3814) is a potent and selective inhibitor of DNA-dependent Protein Kinase (DNA-PK), with an IC50 of <3 nM.
VX984 Chemical Structure
 BCP29470 VX984 1476074-39-1
VX984 is a DNA-PK inhibitor.
VX-984 Chemical Structure
 BCP29319 VX-984 1562396-65-9
VX-984 is a selective DNA-dependent protein kinase (DNA-PK) inhibitor with IC50 of 88±64 nM for A549 lung cancer cells.
PIK-75 Chemical Structure
 BCP01968 PIK-75 372196-67-3
PIK-75, free base is a selective inhibitor of PI 3-kinase p110α (IC50 values are 5.8, 76 nM and 1.3 μM at PI 3-kinase p110α, PI 3-kinase p110γ and PI 3-kinase p110β respectively).
PIK-75 Hydrochloride Chemical Structure
 BCP14766 PIK-75 Hydrochloride 372196-77-5
PIK-75 is a DNA-PK and PI3K inhibitor, which inhibits DNA-PK, p110α and p110γ with IC50s of 2, 5.8 and 76 nM, respectively.
PIK75 Chemical Structure
 BCP27614 PIK75 945619-31-8
PIK-75 is a DNA-PK and PI3K inhibitor, which inhibits DNA-PK, p110α and p110γ with IC50s of 2, 5.8 and 76 nM, respectively.
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